The famous nocturnal Hex hatch of the Midwest (and a few other lucky locations) stirs to the surface mythically large brown trout that only touch streamers for the rest of the year.
To determine whether a specimen of Ephemeroptera belongs to Isonychiidae, use the Key to Families of Mayfly Nymphs or Key to Families of Mayfly Duns and Spinners.
Some Isonychia species are multibrooded, but not in the same way as most other multibrooded mayflies like the Baetidae. In those species, the flies emerging in midsummer or Fall are the offspring of the earlier hatch from the same year. In Isonychia, the Fall emergers are offspring from the previous Fall. They are present as half-grown nymphs when the first of their generation emerge. Although Isonychia broods have distinct peaks, some may be found on the water at any time in between.