Welcome, Jim, I spent many happy years in Chapel Hill. Yes, it is confusing to sort everything out you hear when you're first beginning. And sometimes when you've been at it a while. The first thing you might try is asking at a fly shop where the folks know the stream. They should be able to suggest a few basic flies to start out with any time of year. If that is not feasible, perhaps this will help: most trout streams have mayflies, midges, and caddis in them, and although I have boxes and boxes of flies, I often start off nymphing with a simple bead head hare's ear. If you tie, you don't need any tails, ribbing, etc. In the right size (generally bigger for higher, faster, or more cloudy water, smaller for lower, slower, or clear water) this fly, with a dead drift, will often catch fish. I tie most of mine with a small fluorescent orange hot spot just behind a gold bead in all sizes, and typically fish that fly, but sometimes I'll use a version with no hot spot if I think the fish may be spooked by it. I've caught plenty of browns in low clear water with the hot spot version of this fly (called a Walt's Worm in Pennsylvania) in a size 18-22. I also like a plain black, silver bead, zebra midge ribbed with silver wire, especially in waters where midge activity is significant. Match size (and color if needed) to the midges you see flitting about. I just started using this fly a season or two ago, and have been surprised by how effective it is. Another good all purpose nymph is the green weenie, or inchworm. Eric Stroup, a guide on the Little Juniata, once told me he's seen fish swim across the stream to eat this fly. Size is often important, though sometimes a big fly will work in lower clear water. Drift is the key. I'm also partial to the Iron Lotus. Google it. I fish in in many sizes, but mostly smaller ones (16-20) and it's deadly when olives are hatching, or as all around attractor mayfly nymph. It can be tied to represent other hatches, too. With dries, I try to match the hatch, or use terrestrials. But perhaps that's something for another post. Bottom line, you can start with a relatively simple fly selection and catch fish in just about any stream, especially in the freestone streams of the Appalachian mountains near your neck of the woods. (Spring creeks sometimes call for other flies, though.) As my friend Westbranch says in another thread, casting and line management skills are critical, often more so than fly selection. Learn these and use these basic flies and you'll be sure to catch fish in many trout streams any time of year.
"He spread them a yard and a half. 'And every one that got away is this big.'"
--Fred Chappell