The famous nocturnal Hex hatch of the Midwest (and a few other lucky locations) stirs to the surface mythically large brown trout that only touch streamers for the rest of the year.
This one seems to lead to Couplet 35 of the Key to Genera of Perlodidae Nymphs and the genus Isoperla, but I'm skeptical that's correct based on the general look. I need to get it under the microscope to review several choices in the key, and it'll probably end up a different Perlodidae.
This genus historically contained only one species of interest to anglers, Labiobaetis propinquus. However, many species formerly in other genera including Pseudocloeon have since been moved into Labiobaetis.
Where & when
In 34 records from GBIF, adults of this genus have mostly been collected during June (41%), July (24%), August (18%), May (9%), and October (6%).
In 66 records from GBIF, this genus has been collected at elevations ranging from 335 to 11401 ft, with an average (median) of 4232 ft.